Hydrochloroquine Update

I feel compelled to make this one final substantive post because it gives me an opportunity to combine my posting of source materials and, to the extent that I can replicate it, Mark’s love of snark.

The FDA has posted a warning about the use of hydrochloroquine.  Here’s a link to the warning.

The Journal of the American Medical Association has an editorial about hydrochloroquine and a Brazilian study that was terminated early due to adverse consequences to the patients.  The editorial states:

Several other trials, including a large multicenter trial in the US, are ongoing and hopefully will provide additional crucial information about the efficacy and safety of hydroxychloroquine. In the interim, the results of [the Brazilian study] should prompt some degree of skepticism toward the enthusiastic claims about chloroquine and perhaps serve to curb the exuberant use. For the time being, prudent clinicians should discuss with patients and their families, when feasible, the potential risks of this drug and the uncertain benefits before initiating it.

Here’s a link to a single file that contains the JAMA editorial and the paper on the Brazilian study.

Here’s the snark:  I don’t know whether the trials referred to in the JAMA editorial use hydrochloroquine alone or in conjunction with the use of Lysol.

I think that Mark would have liked that.